You can find a number of safes with various kinds of loot within each mission. Its a good idea to unlock any safes you come across since you can find incredibly valuable items most of the time.
When opening safes, keep in mind that many combinations you find in both in writings (like documents) and some written in the world are randomized. This means they will be different each time you play through the mission and try to open the safe associated with it. Safes are only found in the first three missions of the game.
For this reason, we have written where to obtain these combinations in place of an actual static 3-digit number in the article below.
Below is a list of known safes in each mission, as well as the combinations to open them.
After taking out the first group of guards, look up above the train tracks for a balcony to a residence, and use the pipes up on the left side to enter the home. Inside, you can find a safe against the wall by the door - but no apparent clues for the combination are nearby.
Once you are in the Albarca Baths fight club, look for the Bookkeeper by the restricted area and pickpocket him to get a note with a clue about the safe: there are stacks of books that reveal the clue.
Now that you have the note about the safe, head to the main desk and look above the Champion Challenge board for stacks of books divided into three piles. The number of books in each pile is the combination to the safe (which, if static, is 451), which holds a ton of goods - a 395 coin value, and a health potion!
There are three safes with combinations in Mission 2
There's a safe in the office of the journalist who lives across the plaza from the bank. In order to get the combination, you need to help him implicate Ivan Jacobi in the murder of Cienfuegos.
Once you have the key from Ivan, enter his office and look for a painting of an owl, and move it aside to find a vial of Cienfuegos blood. Give it to the journalist and he'll give you the combination.
While not technically a safe, the door to the Black market is locked with a three digit code. To get the code, look for a hole in a grate behind a sign, and use Foresight to travel through the grate to get into the black market shop. Look at the door from behind to find the code to get in.
The final safe is in the home of Shan Yun, in his study on the third floor. However, his safe does not have a combination, but can only be accessed by using his voice singing the correct song.
In order to find the correct song, head to the private gallery on the second floor, and steal the gold audiograph and play it on the audiograph player next to the safe.
There are four Safes in Mission 3 with combination locks
The first of three sealed lockboxes in the Archives area, located in the sub-basement of the Inner Atrium, can be found in a small room with the other lockboxes.
This lockbox belongs to Christopher Jeorge, the journalist. You can find the code for this lockbox by searching the office of the Operations Manager back on the third floor of the Lobby, and look for a crumpled note by the desk.
The second of three sealed lockboxes in the Archives area, this safe belongs to Morgan Yu. It is part of the Rags to Riches to Rags Contract, and checking the contract, the person states they told everyone how much money they had when they first arrived at Karnaca, which is the code to the lockbox.
The third sealed lockbox in the Archive area belongs to Dr. Galvani, the unfortunate soul you've been robbing for the better part of two games now.
A note in the Office of the Financial Controller, located on the back part of the Inner Atrium first floor, states that Galvani won't shut up about his code being the most important date in his life. As it happens, you can read his memoir in the sleeping area on the other side of the Archives Room, which mentions a date and month.
Use the calendar outside the room with the memoir to match the month, and use its place on the chart for the last number in the combination to open the lockbox.
The last safe, which is in fact five safes all tied to one giant combination, can be found in the Main Vault.
When you first enter the bank, on the third floor stairwell, be sure to check the side door to find a storage room with a chalkboard full of numbers. The note on the board is about the Vault Safe Code, and states that there are a sequence of numbers, and each number is generated by the number before it - but the method they are generated is unknown.
Those familiar with math will recognize the drawings as the Fibonacci sequence - the sequence of numbers where the next number in the sequence can be found by adding the current and previous numbers.
Once you unlock the Main Vault, you'll find 6 safe boxes - one of which needs two keys, while the rest have 3-digit codes. The numbers on the blackboard are the first half of the sequence, which translates to the first three combinations - but you'll need all of them to open all of the safes at once.
Use the guide below to input each code in the correct order - making sure to skip over the numbers that would have been used in vault 4, where the keyholes are.
Vault Number
|
Combination Sequence
|
Vault 1
|
011
|
Vault 2
|
235
|
Vault 3
|
813
|
Vault 4
|
213 (SKIP)
|
Vault 5
|
455
|
Vault 6
|
891
|
Entering every combination will open all vaults - excluding the one that holds the twin-bladed knife, and has a variety of goods to steal.
There are no safes or locks that require combination in Mission 4.
There are two locks that require combinations in Mission 5.
The first lock you find is attached to a door leading to the Shindaery North Mining Quarry, past two Cultists in the midst of killing a third.
To find the combination, head into the building to the side of the gate, and look for stairs going up to the top floor. Move through the room and look up left for a bit of red cloth hanging from a crawlspace. Crawl through to the other side of the factory to another office, where you can find a Supervisor’s Note with the key to the gate outside.
The second lock is found on a chest in the room of Malchiodi, the cultist who was researching the Outsider and the ancient language of runes used by him. In order to get inside, find his body in the Void and get his key, then return to his room.
Note that the man has drawn the Mark of the Outsider everywhere, especially next to all the smaller runes and tagged them with numbers. Upon close inspection, the Mark of the Outsider is a combination of three runes: the upper left portion, the middle portion, and the right portion.
Find the corresponding runes and numbers, and enter them in left to right on the nearby safe to open it and find a Corrupt Bonecharm - as well as Malchiodi’s Diary.
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